The incident occurred around Shasha market along Akure/Owo road expressway in the early morning of Wednesday.
According to an eyewitness, the driver of the tanker loaded with petroleum product lost control of the vehicle and rammed into two other articulated vehicles.
He said two people, however, died on the spot while five others were seriously injured and were rushed to the hospital in Akure.
Confirming the development, the Deputy Sector Commander of Federal Road Safety Corps (FRSC), Mr Olusegun Ogungbemide, said the accident was caused due to brake failure.
He said: “There was a crash this morning at Shasha Market involving a tanker and two other vehicles.
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“We got information that a tanker had a brake failure and hit a vehicle and entered into a filling station while the other truck, in trying to avoid the tanker, ran into an opposite filling station.
“Two people died at a spot while five injured were rushed to a hospital in Akure.
“So, we are still doing a follow-up but the obstruction is already cleared and the road is free now,” Ogungbemide said.
He called on tanker drivers and other motorists to ensure that their vehicles were in good order before embarking on any journey, especially during the yuletide to avoid road crashes.
“Motorists should try and put their vehicles in order.
“We have been doing the advocacy for long, that when they get to a busy area, they should reduce their speed to the minimum speed limit and have respect for other road users.
“And, this season, motorists should know that activities on the road are high and they should drive with every cautiousness.”