FIGF-1 LR3 Peptide and Muscle Investigations

The topic of this article will revolve around the IGF-1 LR3 peptide. IGF-1 Long R3 is an amino acid that is found in polypeptides. In order to get rid of any extra glucose present throughout the body, growth hormone hGH is naturally converted into IGF 1.

IGF-1 Synthetic protein LR3 is just an extended version of the naturally occurring protein IGF-1. The original IGF-1 included glutamic acid, whereas LR3 has arginine in the third position of its amino sequence (thus the name “R3”), which is the main difference. It also includes thirteen more amino acids at its N-terminus, making it substantially longer, for a combined total of eighty-three aminos, as opposed to the seventy that come with IGF-1 alone. This brings up the total number of aminos in the combined molecule to eighty-three.

Researchers have suggested that the potency of IGF-1 LR3 may be about three times more than that of IGF-1 [i], and it may have a much longer half-life, which is around twenty to thirty hours, in comparison to the original IGF-1, which only has a half-life of approximately twelve to fifteen hours.

IGF-1 LR3 versus LR2

Studies suggest that even though they have similar chemical and structural characteristics, IGF-1 LR3 and LR2 are not interchangeable. Researchers speculate the primary distinction between the two is that IGF-LR3 is more often found in mature animals. At the same time, LR2 is more prevalent in younger species, particularly those whose internal biological systems are still maturing. Scientists hypothesize it may be understood in this manner why IGF-1 may have such a major influence on the development and regeneration of muscle tissue. The IGF 1-LR3 peptide was created to conduct an extensive research over an extended period to investigate its possible capacity to stop the deactivation of binding proteins in the blood [ii].

IGF-1 LR3 Peptide Research and Clinical Investigations

Various research findings suggest IGF-1 LR3 may have many potential properties. Researchers speculate its key properties may include the potential ability to stimulate lipolysis, which may help with weight reduction as well as the promotion of protein synthesis and regeneration of muscle tissue.

IGF-1 LR3 Peptide and Weight

Studies suggest IGF-1 LR 3 may improve the efficiency of energy metabolism by stimulating cells to become more responsive to insulin. Concurrently, it may also increase the pace at which fat is broken down into parts. Research suggests this metabolic process may result in the release of energy when larger molecules of fat are broken down into smaller ones that are more readily manipulated. All of this is done to provide fuel for vital cellular functions. It appears to do this while conserving glucose levels and increasing the rate muscle tissue metabolizes fat. Studies suggest that, individually, this may result in an increase in the rate of protein synthesis in muscle cells. Scientists hypothesize the end effect may be muscle development, which may occur as a direct consequence of increases in cell size. In addition to the improvements in muscle mass, studies have suggested the peptide may also potentially reduce fat.

IGF-1 LR3 and Muscle

One of the aims of this research was to evaluate the potential effects of IGF-1 LR3 peptide on protein metabolism. In order to get the desired results of this research, the test animals were purposefully underfed and allowed to lose weight. The models were separated into two groups: the test group, which received the peptide, and the control group, which did not receive the compound.

The findings of this study suggested the animals could maintain the protein levels in their skeletal muscles and their bodies as a whole. Recent research has speculated that IGF-1 may act as a modulator of the effects of GH. Therefore, it may be deduced that the majority of the cells in the body could be influenced by whatever IGF-1 may accomplish. IGF-1 production is often considered to reach its peak during the period when a young organism is going through the process of puberty. This is why a young organism undergoing this process has a considerable growth spurt in height and muscular mass.

Compounds used in scientific research should never be used outside of a laboratory, and human/personal use is strictly prohibited. You can find IGF-1 LR3 for sale if you are a verified professional or active scientist.

References

[i] Tomas M, et al. “Superior potency of infused IGF-I analogues which bind poorly to IGF-binding proteins is maintained when administered by injection.” 1996.

[ii] Oliver T., et al. “The local expression and abundance of insulin-like growth factor (IGF) binding proteins in skeletal muscle are regulated by age and gender but not local IGF-I in vivo.” 2005