What is SC genotype?

doctorsThank you for your good works. Please what is SC genotype? How many Nigerians have this kind of genotype?

James (by SMS)

Hemoglobin SC disease, is a type of sickle cell disease, which means it affects the shape of the red blood cells. Red blood cells contain a protein called hemoglobin, which is responsible for carrying blood throughout the body. People with hemoglobin SC disease have red blood cells that are differently shaped and therefore do not carry oxygen as effectively. Symptoms of hemoglobin SC disease include anemia and episodes of fatigue and extreme pain (vaso-occlusive crisis). The severity of the symptoms can vary from person to person. People affected by hemoglobin SC disease need to be especially careful to avoid infection and should be checked regularly by doctors to make sure all of the organs in the body are functioning properly. In times when the anemia becomes severe, a person affected by hemoglobin SC disease may require a blood transfusion. A bone marrow transplant may also be recommended depending on the severity of the symptoms. The long-term outlook for people affected by hemoglobin SC disease can vary depending on the severity of symptoms. Some people are minimally affected by the condition while others have more serious complications of the disease and may have require blood transfusions when the anemia becomes severe.

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