Ask the Doctor

Genotype as and malaria

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I want to know if it is true that Genotype AS protects the bearer from having Malaria fever.

Akeem (by SMS)

Yes, it is true that people with AS genotype (sickle cell trait) have partial protection against severe malaria, especially *Plasmodium falciparum, the most dangerous species. Their red blood cells are slightly altered, making it harder for the malaria parasite to grow and multiply.

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Tags: genotype malaria

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